Sestu is part of the metropolitan city of Cagliari, an ancient rural village submerged by modern building expansion which still retains some evidence of the past.
The oldest human settlements date back to the third millennium BC.
The name of the city dates back to Roman times and derives from the position it occupied along the road that leads from Cagliari to Porto Torres: ad sextum lapidem.
Lying on a flat valley floor, beyond the bridge over the Rio is Cannas, the oldest part of the town is located, characterized by the frequent succession of typical Campidanese houses.
In a small square in the center of the district stands the parish church of the town, built in 1567 in honor of St. George in the Gothic-Catalan style, in the most common form in the Campidano: a crenellated horizontal crowning facade flanked by buttresses, with oculus ( once decorated with a rose window) on the pointed arch portal; The square-barreled bell tower is also original, with a belfry open from mullioned windows; the single-nave interior has well-preserved chapels and apse (square and covered with a star vault).
In the town there is also the thirteenth-century church of S. Salvatore, with three naves, with decorative motifs engraved on the ashlar facing of the facade
